July 11, 2005

Stem cell debate

I thought that I'd inject a little bit of reality into the stem-research debate. Below is the list of disorders that stem cells are used to either treat or cure:


Acute Leukemia’s
Acute Lymphoblast Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Biphenotypic Leukemia
Acute Undifferentiated Leukemia


Chronic Leukemia’s
Chronic Myelogenous Leukemia (CML)
Chronic Lymphocytic Leukemia (CLL)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)


Myelodysplastic Syndromes
Refractory Anemia (RA)
Refractory Anemia with Ringed Sideroblasts (RARS)
Refractory Anemia with Excess Blasts (RAEB)
Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
Chronic Myelomonocytic Leukemia (CMML)


Stem Cell Disorders
Aplastic Anemia (Severe)
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pure Red Cell Aplasia


Myeloproliferative Disorders
Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (myelofibrosis)
Polycythemia Vera
Essential Thrombocythemia


Lymphoproliferative Disorders
Non-Hodgkin's Lymphoma
Hodgkin's Disease


Phagocyte Disorders
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis


Other Inherited Disorders
Lesch-Nyhan Syndrome
Cartilage-Hair Hypoplasia
Glanzmann Thrombasthenia
Osteopetrosis
Adrenoleukodystrophy

Inherited Platelet Abnormalities
Amegakaryocytosis / Congenital Thrombocytopenia

Inherited Metabolic Disorders
Mucopolysaccharidoses (MPS)
Hurler's Syndrome (MPS-IH)
Scheie Syndrome (MPS-IS)
Hunter's Syndrome (MPS-II)
Sanfilippo Syndrome (MPS-III)
Morquio Syndrome (MPS-IV)
Maroteaux-Lamy Syndrome (MPS-VI)
Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
Adrenoleukodystrophy
Mucolipidosis II (I-cell Disease)
Krabbe Disease
Gaucher's Disease
Niemann-Pick Disease
Wolman Disease
Metachromatic Leukodystrophy

Histiocytic Disorders
Familial Erythrophagocytic Lymphohistiocytosis
Histiocytosis-X
Hemophagocytosis

Inherited Erythrocyte Abnormalities
Beta Thalassemia Major
Sickle Cell Disease

Inherited Immune System Disorders
Ataxia-Telangiectasia
Kostmann Syndrome
Leukocyte Adhesion Deficiency
DiGeorge Syndrome
Bare Lymphocyte Syndrome
Omenn's Syndrome
Severe Combined Immunodeficiency (SCID)
SCID with Adenosine Deaminase Deficiency
Absence of T & B Cells SCID
Absence of T Cells, Normal B Cell SCID
Common Variable Immunodeficiency
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

Plasma Cell Disorders
Multiple Myeloma
Plasma Cell Leukemia
Waldenstrom's Macroglobulinemia
Amyloidosis

Other Malignancies
Ewing Sarcoma
Neuroblastoma
Renal Cell Carcinoma
Retinoblastoma

As an FYI: all of the treatments above use adult stem cells. Currently, no embryonic stem cell research has reached the clinical trial phase.

Posted by Physics Geek at July 11, 2005 03:58 PM | TrackBack StumbleUpon Toolbar Stumble It!
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